Vaxzevria (AstraZeneca) vaccine and thrombosis with thrombocytopenia (TTS) | Australian Government Department of Health, Disability and Ageing

Your blood can clot so that you don't lose too much blood if you are injured. But blood clotting can become a problem when it stops blood flow through your blood vessels.
A blood clot in a blood vessel is called a thrombus. It can be life-threatening if it's not treated quickly. Blood clots can lead to problems such as a:
If you think you may have a blood clot, see your doctor as soon as possible.

Blood clotting can become a problem when it stops your blood from flowing properly.
Blood clots can cause different problems depending on where they are in your body.
The following conditions are caused by blood clots in blood vessels (arteries or veins) in different parts of the body.
A DVT is when a blood clot forms in one of the veins deep inside your body. DVTs mostly occur in your legs, but you can get a DVT anywhere in your body.
The most common symptoms of DVT are:
Sometimes there are no symptoms.
If a blood clot travels from a deep vein to blood vessels in your lungs, it's called a pulmonary embolism.
Symptoms of a pulmonary embolism are:
A pulmonary embolism can be life-threatening.
A blood clot in blood vessels in your brain can cause a stroke.
Symptoms of a stroke can include:
A blood clot in the blood vessels that supply your heart (coronary arteries) can lead to a heart attack.
Symptoms of a heart attack can include:
A blood clot in a blood vessel (thrombus) can happen when:
Blood flow in your leg veins can slow down if you sit or lie still for a long time.
Often, a combination of things leads to a blood clot.
You are more likely to develop a DVT if:
Other factors that can increase your risk of a DVT are:
Having atherosclerosis (a build-up of cholesterol and other material in the walls of your arteries) increases your risk of blood clots that can cause heart attack and stroke.
Blood clots can cause serious complications. See your doctor as soon as possible if you think you may have a blood clot.
Your doctor will ask you about your symptoms, overall health and lifestyle. They will also examine you.
Tests that can help diagnose a blood clot will depend on your symptoms and the part of your body that's affected. Your doctor may recommend:
Treatment for a blood clot will depend on its location.
One treatment for blood clots is anticoagulant medicines (blood thinners). These medicines stop blood clots from growing larger and prevent new clots from forming.
You may need to take blood thinners for several months or longer. Regular follow up is needed with your doctor to check that the treatment is working.
Sometimes blood clots are treated with a medicine or procedure to:
If you have a DVT, compression stockings may help with your symptoms and improve the blood flow in your legs.
If you have a heart attack, stroke or pulmonary embolism, you will need to have emergency treatment in hospital.
Some conditions or activities can put you at increased risk of blood clots. Your doctor may recommend medicines or other treatments to reduce your risk of blood clots.
You can also help lower your risk by:
Long-distance travel can increase your risk of getting a DVT. To reduce your risk of blood clots during long-distance travel, try:
Ask your doctor about whether compression stockings are a good idea when travelling.
To reduce your risk of conditions such as heart attack and stroke, your doctor may recommend lifestyle measures. These can include:
Thrombosis Australia (Opens in new tab) has more information on blood clots (thrombosis).
The Heart Foundation (Opens in new tab) and Stroke Foundation (Opens in new tab) have information on heart attack and stroke, including information in languages other than English.
If you want to know more about blood clots or need advice on what to do next, you can call the healthdirect helpline on 1800 022 222 (known as NURSE-ON-CALL in Victoria). A registered nurse is available to speak with 24 hours a day, 7 days a week.
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Last reviewed: May 2025










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